Women 'fight off disease hastalık better' - Kadınlar hastalıktan daha çabuk kurtuluyorlar
Men really do have an excuse for supposedlysözümonabeing wimpyzayıf, çelimsizabout coughsöksürükand coldssoğuk algınlığı - their immune systems are not as strong as women's, research suggests.
A Canadian study indicates göstermek that the female sex hormone oestrogen gives women's immune bağışıklık systems added bite at fighting off infection. Oestrogen seems to counter karşı koymak an enzyme which blocks the inflammatory process.
The McGill University study appears in Proceedings of the National Academy of Sciences.
The researchers focused on an enzyme called Caspase-12, which is known to put a brake fren on the inflammatory iltihaplı process ilerleme, the body's first line of defence against harmful invaders istilacı such as bacteria and viruses.
They worked on mice fareler that lacked yoksun olmak the Caspase-12 gene, and were thus extremely resistant to infection. The human Caspase-12 gene was implanted aşılamak into a group of male erkek and female dişi mice, but only the males became more prone meyilli to infection. The researchers concluded sonuç çıkarmak that oestrogen produced by the female mice blocked the expression of the human Caspase-12 gene. They were also able to locate the precise place where oestrogen binds to the gene in order to block its activity.
Since the experiments were conducted yönetilmek using a human gene, the researchers are confident their work is applicable to humans. Lead researcher Dr Maya Saleh said: "These results demonstrate göstermek that women have a more powerful inflammatory response than men." The researchers believe women may have evolved geliştirmek; gelişmek a more robust kuvvetli immune system because of their key role in producing and nurturing beslemek young.
Their work raises artırmak the possibility of new ways to reinforce güçlendirmek the immune system using genetic manipulation hile. But writing in the journal, the researchers said: "A question remains: will men be amenable boyun eğerek to the idea of being treated davranmak with an exclusively özellikle; sadece female hormone?"
Dr Lesley Knapp, of the University of Cambridge, said there was a substantial kıymetli; önemli body of evidence kanıt to show that women were better at fighting infections than men. She said: "Women are well known to be able to respond more robustly to infections, and to recover iyileşmek more quickly than men." "In evolutionary terms it only takes one male to reproduce with lots of females, but females are much more important in terms of producing offspring evlat.."
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